Oncology
Proven Track Record in
Complex Oncology Clinical Trials
Oncology trials demand precision and adaptability with tight milestone deadlines. REV Clinical pairs our execution with the services, expertise, and clinical network needed to activate high-performing sites, recruit and retain patients, and meet the escalating challenges of complex endpoints and regulatory demands.
Oncology Clinical
Study Capabilities
REV collaborates with leading pharmaceutical partners on the most advanced trial designs in oncology, then executes studies end-to-end—from first-in-human to pivotal and post-market—with rigorous oversight and multi-region operations that accelerate enrollment, maintain quality, and streamline submissions.
- FIH, Phase I & II studies
- Dose escalation studies (SAD/MAD)
- PK/PD interaction studies
- Biosimilar studies
- Phase III and Phase IV studies
- PMS studies
- Patient registry trials
- Concept designing, regulatory strategy drafting & FDA communications
- Confirmatory phase III studies
- Clinical endpoint studies
- Pilot studies
- Pivotal studies
- Human factor studies
- Significant risk (SR) studies
- Non-significant risk (NSR) studies
Experience with
a Wide Range of
Oncology Trials
With deep experience spanning oncology therapeutics and medical devices, REV delivers the flexibility, insight, and precision needed to execute studies across a full spectrum of oncology trial types.
- Breast cancer
- Lung cancer
- Melanoma
- Ovarian cancer
- Prostate cancer
- Pancreatic cancer
- Bladder cancer
- Head & neck cancer
- Glioblastoma
- Renal cell carcinoma
- Colorectal cancer
- Gastrointestinal stromal tumors
- Acute myeloid leukemia
- Chronic myeloid leukemia
- Myelodysplastic syndrome
- Non-Hodgkin’s lymphoma
- Multiple myeloma
KOL-Guided,
Community
Center-Powered
Oncology Trials
The competition for oncology clinical trial patients is fierce, and time is of the essence. Eighty percent of clinical trials are conducted at 20% of sites, with large academic centers employing well-known principal investigators (PIs) comprising the majority of these sites. This clustering creates difficulties in recruiting the patients needed to conduct life-saving research, while community center PIs and the patients they serve lack opportunities to participate in studies.
Additionally, legal agreements and other study start-up inefficiencies often delay studies and increase costs. REV addresses oncology clinical trial challenges with a three-prong approach.
KOL-Driven Site Selection
REV’s close collaboration with key opinion leaders (KOLs) at the forefront of oncology clinical research provides its sponsor clients with entry points to leading academic centers and helps secure PI and patient participation in a highly competitive landscape.
Community Center Network
Our dedication to nurturing and expanding relationships with PIs through a community-driven network is not only critical to securing the patients our sponsors need for their studies but also aids in expanding patient access to emerging, potentially life-saving therapeutic options.
Streamlined NDAs & IRB Approval Process
Launching clinical studies at large academic sites is often delayed by institution-specific NDAs and IRB (Institutional Review Board) reviews. REV accelerates by using each site’s preferred NDA template, making only essential edits, and establishing IRB reliance agreements to eliminate redundant reviews. The result is streamlined approvals, fewer bottlenecks, and faster first-patient-in, without compromising compliance.
Global Velocity Network Facilitates Strategic Market Access for Oncology Trials
Pre-Study Rigor Delivers Faster Starts & Fewer Change Orders for Oncology Trials
Expert Oncology Biostatistics & Clinical Data Management
Oncology Study
Start-Up Services
Perhaps you are waiting for regulatory approvals, additional funding, or the completion of intellectual property filings. REV’s oncology study start-up services can be offered as a standalone service, separate from the operational plan, so that you’ll be positioned to rapidly secure your first patient when you are ready.
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Regulatory, Quality & Compliance Excellence
REV Clinical’s dedication to excellence is grounded in rigorous process governance, compliance, and an understanding of the regulatory frameworks of the world’s leading regulators.
Let’s Move Your Study Forward
Interested in connecting with REV Clinical’s team of interdisciplinary experts to answer questions, take action on your RFP, and clearly define next steps?