Neurology
Precision Operations for
High-Stakes Neurology Trials
Neurology trials, particularly those addressing urgent conditions such as stroke and amyotrophic lateral sclerosis (ALS), require close collaboration with leading academic centers and their principal investigators (PIs). REV Clinical pairs its execution services with deep scientific expertise, KOLs, and the clinical site network needed to secure patients when time is of the essence.
Neurology
Clinical
Study Capabilities
REV executes neurology studies end-to-end—from first-in-human through pivotal and post-market—through adaptive design, rigorous oversight, and multi-region operations that accelerate enrollment, uphold quality, and streamline submissions.
- FIH, Phase I & II studies
- Dose escalation studies (SAD/MAD)
- PK/PD interaction studies
- Biosimilar studies
- Phase III and Phase IV studies
- PMS studies
- Patient registry trials
- Concept designing, regulatory strategy drafting & FDA communications
- Confirmatory phase III studies
- Clinical endpoint studies
- Pilot studies
- Pivotal studies
- Human factor studies
- Significant risk (SR) studies
- Non-significant risk (NSR) studies
Experience with
a Wide Range of
Neurology Trials
With deep experience spanning neurology therapeutics and medical devices, REV delivers the flexibility, insight, and precision needed to execute studies across a full spectrum of neurology trial types.
- Acute ischemic stroke
- Amyotrophic lateral sclerosis
- Multiple sclerosis
- Parkinson’s disease
- Epilepsy
- Refractory complex partial seizures
- Diabetic neuropathy
- Myasthenia gravis
- Schizophrenia
- Bipolar disorder
KOL-Guided
Neurology Trials
Lead to Study
Success
Because time is often critical when selecting and enrolling patients for neurology trials, it is essential to have close relationships with leading academic centers and their PIs, fully understand the site’s standard of care, and be aware of the site’s overall infrastructure.
In addition to the challenge of staging neurology clinical trials to succeed, given the split-second decisions that need to be made when a stroke patient, for instance, is en route to the hospital, legal agreements and other study start-up inefficiencies often delay studies and increase costs. REV addresses neurology clinical trial challenges with a two-prong approach.
KOL-Driven Site Selection
REV’s close collaboration with key opinion leaders (KOLs) at the forefront of neurology clinical research provides its sponsor clients with entry points to leading academic centers and secures PI and patient participation within a highly competitive patient enrollment landscape.
Streamlined NDAs & IRB Approval Process
Launching clinical studies at large academic sites is often delayed by institution-specific NDAs and IRB (Institutional Review Board) reviews. REV accelerates by using each site’s preferred NDA template, making only essential edits, and establishing IRB reliance agreements to eliminate redundant reviews. The result is streamlined approvals, fewer bottlenecks, and faster first-patient-in, without compromising compliance.
Global Velocity Network Facilitates Strategic Market Access for Neurology Trials
Pre-Study Rigor Delivers Faster Starts & Fewer Change Orders for Neurology Trials
Expert Neurology Biostatistics & Clinical Data Management
Neurology Study Start-Up Services
Perhaps you are waiting for regulatory approvals, additional funding, or the completion of intellectual property filings. REV’s neurology study start-up services can be offered as a standalone service, separate from the operational plan, so that you’ll be positioned to rapidly secure your first patient when you are ready.
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Regulatory, Quality & Compliance Excellence
REV Clinical’s dedication to excellence is grounded in rigorous process governance, compliance, and an understanding of the regulatory frameworks of the world’s leading regulators.
Let’s Move Your Study Forward
Interested in connecting with REV Clinical’s team of interdisciplinary experts to answer questions, take action on your RFP, and clearly define next steps?